En esta entrada se irán colocando diversos mecanismos de acción que han sido preguntados en el ENARM.
Haloperidol: is a butyrophenone antipsychotic that nonselectively blocks postsynaptic dopaminergic D2 receptors in the brain.
Metronidazol: interacts with DNA to cause a loss of helical DNA structure and strand breakage resulting in inhibition of protein synthesis and cell death in susceptible organisms.
Metotrexato: irreversibly binds to and inhibits dihydrofolate reductase, inhibiting the formation of reduced folates, and thymidylate synthetase. Is cell cycle specific for the S phase.
Diazepam: Binds to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron at several sites within the central nervous system, including the limbic system, reticular formation. Benzodiazepine receptors and effects appear to be linked to the GABA-A receptors. Benzodiazepines do not bind to GABA-B receptors.
Nistatina: Binds to sterols in fungal cell membrane, changing the cell wall permeability allowing for leakage of cellular contents.
Con información de: UpToDate.